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You should not use this medication if you are allergic to any other ACE inhibitor, such as benazepril Lotensin, captopril Capoten, fosinopril Monopril, enalapril Vasotec, moexipril Univasc, perindopril Aceon, quinapril Accupril, ramipril Altace, or trandolapril Mavik. Before taking hydrochlorothiazide and lisinopril, tell your doctor if you have kidney disease or are on dialysis, liver disease, glaucoma, congestive heart failure, gout, lupus, diabetes, or an allergy to sulfa drugs or penicillin.
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Do not take lisinopril and hydrochlorothiazide if you are pregnant. Lisinopril and hydrochlorothiazide may harm the fetus. The combination of lisinopril and hydrochlorothiazide is used to treat high blood pressure. It works by decreasing certain chemicals that tighten the blood vessels, so blood flows more smoothly. It works by causing the kidneys to get rid of unneeded water and salt from the body into the urine.