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Gwendolyn A. McMillin, Matthew D. Topiramate was first approved in the United States in for treatment of epilepsy. Topiramate has high bioavailability and low binding to serum proteins. TDM of topiramate can be especially helpful due to the variable liver metabolism, especially when topiramate is used concomitantly with medications that alter liver enzyme metabolism.
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The Drug is prescribed to treat epileptic syndrome, migraine, tonic-clonic seizures seizures affecting the whole brain and Lennox-Gastaut syndrome LGS. The drug is used to treat epilepsy at initial stage, migraine and relieve seizures. Topamax has spasmolytic, https://www.kroger.com analgesic and anti-inflammatory effect. Topamax is highly rated as an efficient drug to remove convulsive activity as well as nervous irritability. The drug is absorbed quickly and effectively.
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