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Applies to carbamazepine : oral capsule extended release, oral suspension, oral tablet, oral tablet chewable, oral tablet extended release. Do not start carbamazepine in patients who test positive for the allele unless the benefit clearly outweighs the risk. Discontinue if you suspect that the patient has a serious dermatologic reaction. Aplastic anemia and agranulocytosis have also been reported. Consider drug discontinuation if significant bone marrow depression develops.

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Robert M. Over 2 decades, carbamazepine has become a well-established, off-label alternative to lithium for treating acute mania.

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