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Maybe you accidentally dropped your antidepressant pill while you were taking out your daily dose and your dog, always on the lookout for a tasty treat, ate it. Or perhaps you came home to find that your dog had chewed through the bottle and it's a slobbery mess. The first thing you need to know is that this situation is actually pretty common. While antidepressants are sometimes prescribed for dogs, the doses that humans take can be very toxic to pets, especially if they are smaller animals or they have ingested multiple pills. Restlessness and agitation are the most common signs of antidepressant poisoning in dogs, but they also might experience vomiting, diarrhea, seizures, fever, tremors, sensitivity to noise, decreased heart rate, dilated pupils, vocalization, blindness, drooling, problems with breathing, problems with walking, disorientation, loss of consciousness, and coma.