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Push Health can help connect people who need to use spironolactone with medical providers in their area who can prescribe spironolactone if it is safe and appropriate to do so. Part of a class of medications known as potassium-sparing medications, spironolactone is an antagonist of aldosterone and causes the excretion of sodium and water and the retention of potassium. Through this mechanism, spironolactone is both a diuretic and a medication with antihypertensive effects on both the systolic and diastolic blood pressures. Spironolactone also has antiandrogenic effects and can block androgen hormones such as testosterone. Some people may have heard of other uses, such as spironolactone for weight loss, spironolactone for hair loss or spironolactone for PCOS. As an antiandrogen, spironolactone can cause effects similar to estrogen and can cause gynecomastia.

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