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Treatment of allograft rejection resistant to treatment with other immunosuppressive medicinal products. Prograf therapy requires careful monitoring by adequately qualified and equipped personnel. The medicinal product should only be prescribed, and changes in immunosuppressive therapy initiated, by physicians experienced in immunosuppressive therapy and the management of transplant patients. Prograf dosing should primarily be based on clinical assessments of rejection and tolerability in each patient individually aided by blood level monitoring see below for recommended target whole blood trough concentrations. If clinical signs of rejection are apparent, alteration of the immunosuppressive regimen should be considered.
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Controlled Substance. Tacrolimus is a generic medication used to prevent the rejection of a kidney, heart or liver transplant.
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