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Based on this, one could speculate that increasing the alternate day dosing of rosuvastatin to 40 mg would provide equivalency to 10 mg of rosuvastatin administered on a daily basis; however, further study would be needed to confirm this postulate. A previous study was able to achieve comparable LDL-C reductions with alternate day dosing and daily dosing regimens using a titration strategy, whereby atorvastatin was titrated as necessary to achieve target LDL-C reductions Whether a 7.
However, despite the fact that the alternate day dosing regimen was less effective than the daily dosing regimen, the alternate day dosing regimen still provided an LDL-C reduction of A simpler approach to cost conservation would be to administer rosuvastatin on alternate days, at double the strength. Alternate day dosing would result in reducing costs significantly. Another potential option would be to prescribe a 20 mg tablet of rosuvastatin and advise the patient to split the tablets in half This is Although not as efficacious as daily dosing, alternate day dosing may be a practical solution for those patients with limited financial resources without compromising the clinical benefits of lipid lowering.
The patients in the present study were not blinded.