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DOI: PMID: The addition of ovarian function suppression OFS for 5 years to tamoxifen TAM for treatment of premenopausal patients with breast cancer after completion of chemotherapy has beneficial effects on disease-free survival DFS. This study evaluated the efficacy of adding 2 years of OFS to TAM in patients with hormone receptor—positive breast cancer who remain in a premenopausal state or resume ovarian function after chemotherapy. Ovarian function was assessed every 6 months for 2 years since enrollment on the basis of follicular-stimulating hormone levels and vaginal bleeding history. DFS was defined from the time of enrollment to the time of the first event.

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Tamoxifen blocks the actions of estrogen, a female hormone. Certain types of breast cancer require estrogen to grow.

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I am a male with breast cancer undergoing this treatment and I'm not sure how I'm supposed to feel but it doesn't feel normal. Can you help? This is an important question and one that is not asked often, because of the rarity of male breast cancer.


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