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Sections without translation will be in English. Akerlund Methods. Inclusion: regularly occurring menstrual pain requiring medication Exclusion: lactation; history or sign of severe generalised https://www.telegraph.co.uk allergic or gastrointestinal disease; use of analgesics Age: range 17 to 45, median 26 Location: Sweden. Ketoprofen mg Naproxen mg Single dose Duration: 2 cycles, 1 treatment per cycle. The ketoprofen group initially had higher pain levels Data on adverse effects reports number of symptoms but not number of women affected. Inclusion: primary dysmenorrhoea Exclusion: menstrual irregularities; history peptic ulcer, renal or blood disorders; pregnant; use of other medicines for condition Age: 17 to 33, mean Piroxicam 20 mg, placebo 2 tablets per day for 2 days, then 1 tablet per day until symptoms or menses subsided Duration: 4 cycles per participant, cycles in total. Indomethacin suppositories mg, 1 to 3 times daily, at onset of symptoms, max. Inclusion: women with primary dysmenorrhoea; no history or evidence of pelvic pathology as judged by clinical and gynaecological examinations Exclusion: pelvic pathology; IUD; history of peptic ulcer or dyspepsia; asthma; breastfeeding Age: 16 to 44, mean SD
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Appendix table A: Calculation of effect sizes for placebo. Global assessment scores categorical reported as continuous scores.
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