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Peripheral vasodilator with a predominant effect on the venous vessels. Antianginal agent. The mechanism of action is associated with the release of the active substance nitric oxide in the smooth muscles of the vessels. Nitric oxide causes the activation of guanylate cyclase and increases the level of cGMP, which ultimately leads to relaxation of smooth muscles. Under the influence of isosorbide dinitrate, arterioles and precapillary sphincters relax to a lesser extent than large arteries and veins. The action of isosorbide dinitrate is mainly associated with a decrease in myocardial oxygen demand due to a decrease in preload dilation of peripheral veins and a decrease in blood flow to the right atrium and afterload decrease in OPS, as well as direct coronary dilating.

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Catalog No. Isosorbide Dinitrate is a medication used for heart failure, esophageal spasms, and to treat and prevent chest pain from not enough blood flow to the heart.

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Isosorbide dinitrate ISDN is a medication used for heart failure, esophageal spasms, and to treat and prevent chest pain from not enough blood flow to the heart. Common side effects include headache, lightheadedness with standing, and blurred vision. Isosorbide dinitrate was first written about in


Richard (taken for 1 to 5 years) 30.06.2017

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What does capricious mean? Test Your Knowledge - and learn some interesting things along the way.


Leonie (taken for 2 to 5 years) 17.07.2019

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First Aid. Hand Sanitisers.


Rudolf (taken for 1 to 4 years) 29.09.2017

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A vasodilator used in the treatment of angina pectoris. Its actions are similar to nitroglycerin but with a slower onset of action. A governmentally-recognized ID which uniquely identifies the product within its regulatory market.


Rahel (taken for 2 to 7 years) 05.06.2019

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