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Common side effect include dry mouth, dizziness, headaches, and sleepiness. Clonidine was patented in and came into medical use in Clonidine is used to treat high blood pressure, attention deficit hyperactivity disorder ADHD, drug withdrawal alcohol, opioids, or smoking, menopausal flushing, diarrhea, and certain pain conditions. Clonidine may be effective for lowering blood pressure in people with resistant hypertension. Clonidine works by slowing the pulse rate and exert a reduction of serum concentrations of renin, aldosterone and catecholamines. Clonidine may improve symptoms of attention deficit hyperactivity disorder in some people but causes many adverse effects and the beneficial effect is modest. Clonidine may be used to ease drug withdrawal symptoms associated with abruptly stopping the long-term use of opioids, alcohol, benzodiazepines and nicotine smoking.
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Clonidine is an imidazole derivate that acts as an agonist of alpha-2 adrenoceptors. Clonidine was granted FDA approval on 3 September A governmentally-recognized ID which uniquely identifies the product within its regulatory market. Clonidine tablets and transdermal systems are indicated for the treatment of hypertension alone or in combination with other medications. Clonidine is also used for the diagnosis of pheochromocytoma, 3 treatment of nicotine dependance, 4 and opiate withdrawal.
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Common side effects include increased weight, sleepiness, and dizziness. Mirtazapine came into medical use in the United States in Mirtazapine is primarily used for major depressive disorder and other mood disorders. In NICE recommended generic SSRIs as first line choices, as they are equally effective as other antidepressants and have a favourable risk—benefit ratio. However, there is strong evidence that patients taking mirtazapine are less likely to leave treatment early because of side effects, although this is not the case for patients reporting side effects or leaving treatment early for any reason.
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